There are 7 ways to get from Madrid to Brindisi by plane, train (Renfe, Ouigo, Trenitalia), bus, car, train (Renfe, Ouigo, TGV, Trenitalia), train, or night train
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly
best- Fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brindisi Airport (BDS)plane MAD - BDS
5h 5m€63–233Train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Lyon Part Dieutrain
- Take the train from Lyon Part Dieu to Torino Porta Susatrain Fr
- Take the train from Torino Porta Susa to Brindisitrain Fr
23h 44m€240–695Bus
- Take the bus from Madrid to Milanbus FlixBus N1138
- Take the bus from Milano, Autostazione Lampugnano to Brindisi Istituto Professionale Falconebus MarinoBus 043 / ...
37h 25m€104–303Drive 2,426.7 km
- Drive from Madrid to Brindisicar 2,426.7 km
24h€379–547Train via Saint-Marcel-lès-Valence
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Santstrain Ave
- Take the train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sudtrain Tgv
- Take the train from Valence Tgv Rhone-Alpes Sud to Chambery Challes Les Eauxtrain Ter
- Take the train from Chambery Challes Les Eaux to Torino Porta Susatrain Tgv
- Take the train from Torino Porta Susa to Brindisitrain Fr
24h 25m€250–850Train, bus, night train
- Take the train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charlestrain
- Take the bus from Marseille, Gare de Marseille-Saint-Charles to Turinbus 404
- Take the night train from Torino Lingotto to Brindisinighttrain Ini
29h 35m€196–297Bus via Turin
- Take the bus from Madrid Mendez Alvaro Estacion Sur to Turin Corso Vittorio Emanuele IIbus Union Ivkoni - Unibus 3417 / ...
- Take the bus from Turin Stura Bus Station to Brindisi Istituto Professionale Falconebus MarinoBus 043
45h 23m€148–271
Madrid to Brindisi by train
Questions & Answers
The cheapest way to get from Madrid to Brindisi is to fly which costs €60 - €240 and takes 5h 5m.
The fastest way to get from Madrid to Brindisi is to fly which takes 5h 5m and costs €60 - €240.
No, there is no direct bus from Madrid to Brindisi. However, there are services departing from Madrid and arriving at Brindisi Istituto Professionale Falcone via Milano, Autostazione Lampugnano. The journey, including transfers, takes approximately 37h 25m.
No, there is no direct train from Madrid to Brindisi. However, there are services departing from Madrid-Puerta de Atocha-Almudena Grandes and arriving at Brindisi via Barcelona-Sants, Lyon Part Dieu and Torino Porta Susa. The journey, including transfers, takes approximately 23h 44m.
The distance between Madrid and Brindisi is 1824 km. The road distance is 2426.7 km.
The best way to get from Madrid to Brindisi without a car is to train which takes 23h 44m and costs €240 - €700.
It takes approximately 5h 5m to get from Madrid to Brindisi, including transfers.
Madrid to Brindisi bus services, operated by FlixBus, depart from Madrid station.
Madrid to Brindisi train services, operated by Renfe AVE, depart from Madrid-Puerta de Atocha-Almudena Grandes station.
The best way to get from Madrid to Brindisi is to fly which takes 5h 5m and costs €60 - €240. Alternatively, you can train, which costs €240 - €700 and takes 23h 44m, you could also bus, which costs €100 - €310 and takes 37h 25m.
What companies run services between Madrid, Spain and Brindisi, Italy?
Ryanair and ITA Airways fly from Adolfo Suárez Madrid–Barajas Airport (MAD) to Brindisi Airport (BDS) once daily. Alternatively, you can take a train from Madrid-Puerta de Atocha-Almudena Grandes to Brindisi via Barcelona-Sants, Lyon Part Dieu, and Torino Porta Susa in around 23h 44m.
- Website
- ryanair.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport
- Ave. Duration
- 2h 50m
- When
- Monday
- Estimated price
- €60–230
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport via Rome
- Ave. Duration
- 5h 12m
- When
- Monday and Friday
- Estimated price
- €60–230
- Website
- ita-airways.com
Flights from Adolfo Suárez Madrid–Barajas Airport to Brindisi Airport via Rome
- Ave. Duration
- 5h
- When
- Every day
- Estimated price
- €65–190
Rome2Rio's guide to Renfe AVE
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 2h 37m
- Frequency
- Hourly
- Estimated price
- €45–180
- Website
- https://www.renfe.com/es/en
- Phone
- +34 900 926 851
- atencion.cliente@iryo.eu
- Website
- iryo.eu
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 2h 57m
- Frequency
- Hourly
- Estimated price
- €40–130
- Website
- https://iryo.eu/en/home
- Phone
- +34 910 780 990
- Website
- ouigo.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 2m
- Frequency
- Every 4 hours
- Estimated price
- €35–75
- Website
- https://www.ouigo.com/es/en
Rome2Rio's guide to Renfe Viajeros
Contact Details
- Phone
- +34 91 232 03 20
- Website
- renfe.com
Train from Madrid-Puerta de Atocha-Almudena Grandes to Barcelona-Sants
- Ave. Duration
- 3h 4m
- Frequency
- Twice daily
- Estimated price
- €45–65
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Lyon Part Dieu
- Ave. Duration
- 5h 6m
- Frequency
- Once daily
- Estimated price
- €50–75
- Website
- https://www.renfe.com/es/en
Train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 4h 29m
- Frequency
- Once daily
- Estimated price
- €45–60
- Website
- https://www.renfe.com/es/en
Train from Madrid-Puerta de Atocha-Almudena Grandes to Marseille St Charles
- Ave. Duration
- 8h 15m
- Frequency
- Once daily
- Estimated price
- €90–130
- Website
- https://www.renfe.com/es/en
- Phone
- +39.06.5210550
- Website
- trenitalia.com
Train from Lyon Part Dieu to Torino Porta Susa
- Ave. Duration
- 3h 57m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 34m
- Frequency
- Twice daily
- Estimated price
- €55–140
- Website
- https://www.trenitalia.com/en.html
- Phone
- +39 06 68475475
- Website
- trenitalia.com
Train from Torino Porta Susa to Brindisi
- Ave. Duration
- 9h 4m
- Frequency
- Once daily
- Estimated price
- €100–300
- Schedules at
- trenitalia.com
- Phone
- +33 1 84 94 36 35
- Website
- sncf-connect.com
Train from Barcelona-Sants to Valence Tgv Rhone-Alpes Sud
- Ave. Duration
- 4h 24m
- Frequency
- Twice daily
- Estimated price
- €35–140
- Website
- https://www.sncf-connect.com/en-en
Train from Chambery Challes Les Eaux to Torino Porta Susa
- Ave. Duration
- 2h 39m
- Frequency
- Twice daily
- Estimated price
- €50–170
- Website
- https://www.sncf-connect.com/en-en
- Phone
- +33 1 84 94 36 35
- Website
- track.effiliation.com
Train from Valence Tgv Rhone-Alpes Sud to Chambery Challes Les Eaux
- Ave. Duration
- 1h 53m
- Frequency
- Hourly
- Estimated price
- €30–60
- Website
- https://track.effiliation.com/servlet/effi.redir?id_compteur=23007591&url=https%3A%2F%2Fwww.sncf-connect.com%2Fen-en%2F
- Phone
- 06 3000
- Website
- trenitalia.com
Night train from Torino Lingotto to Brindisi
- Ave. Duration
- 12h 45m
- Frequency
- Once daily
- Estimated price
- €80–120
- Website
- https://www.trenitalia.com/en.html
- Phone
- +49 30 300 137 300
- service@flixbus.com
- Website
- flixbus.fr
Bus from Madrid to Milan
- Ave. Duration
- 23h 5m
- Frequency
- Once daily
- Estimated price
- €70–160
- Website
- https://www.flixbus.co.uk
Bus from Milano, Autostazione Lampugnano to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 14h 15m
- Frequency
- Once daily
- Estimated price
- €35–140
- Website
- https://www.flixbus.co.uk
Bus from Marseille, Gare de Marseille-Saint-Charles to Turin
- Ave. Duration
- 6h 35m
- Frequency
- Once daily
- Estimated price
- €23–55
- Website
- https://www.flixbus.co.uk
- Phone
- +39 080 3112335
- info@marinobus.it
- Website
- marinobus.it
Bus from Milano, Autostazione Lampugnano to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 13h 20m
- Frequency
- Once daily
- Estimated price
- €65–150
- Website
- https://marinobus.it/en/
Bus from Turin Stura Bus Station to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 14h 50m
- Frequency
- Once daily
- Estimated price
- €70–160
- Website
- https://marinobus.it/en/
- Phone
- +39 06 88 93 82 32
- Website
- itabus.it
Bus from Milano, Autostazione Lampugnano to Brindisi Istituto Professionale Falcone
- Ave. Duration
- 14h 35m
- Frequency
- Twice daily
- Estimated price
- €30–150
- Website
- https://www.itabus.it/en/home
- Phone
- 07001 8282
- booking@union-ivkoni.com
- Website
- union-ivkoni.com
Bus from Madrid Mendez Alvaro Estacion Sur to Turin Corso Vittorio Emanuele II
- Ave. Duration
- 28h 30m
- Frequency
- Twice a week
- Estimated price
- €75–120
- Website
- https://union-ivkoni.com/en
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More Questions & Answers
Madrid to Brindisi bus services, operated by FlixBus, arrive at Milan station.
Madrid to Brindisi train services, operated by Renfe AVE, arrive at Barcelona-Sants station.
Yes, the driving distance between Madrid to Brindisi is 2427 km. It takes approximately 24h to drive from Madrid to Brindisi.
Book your Madrid to Brindisi train tickets online with Omio.
Book your Madrid to Brindisi bus tickets online with Omio and FlixBus.
There are 888+ hotels available in Brindisi.










































