There are 6 ways to get from Louisville to Key West by plane, bus, ferry, car, or bus (Amtrak, Greyhound, Flixbus)
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly from Louisville International Airport
best- Fly from Louisville International Airport (SDF) to Key West International Airport (EYW)SDF - EYW
6h 25m$133–666Bus, ferry
- Take the bus from Louisville, KY to Nashville
- Take the bus from Nashville Bus Station to Tallahassee
- Take the bus from Tallahassee to Fort Myers
- Take the ferry from Fort Myers Beach, FL to Key West, FL
28h 26m$355–523Drive 1,175.1 mi
- Drive from Louisville to Key West1,175.1 mi
21h 52m$215–310Bus to Evansville, fly
- Take the bus from Louisville, KY to Evansville, IN
- Fly from Evansville (EVV) to Key West International Airport (EYW)EVV - EYW
8h 18m$220–889Bus to Covington, fly
- Take the bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Fly from Covington (CVG) to Key West International Airport (EYW)CVG - EYW
6h 38m$183–858Bus
- Take the bus from Louisville, KY to Nashville
- Take the bus from Nashville Bus Station to Atlanta Bus Station
- Take the bus from Atlanta Bus Station to Miami Airport Station
- Take the bus from Miami Airport Station to Big Pine Key
- Take the bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd StreetLks
30h 26m$157–370
Louisville to Key West by bus and foot
Questions & Answers
The cheapest way to get from Louisville to Key West is to bus which costs $150 - $370 and takes 30h 26m.
The fastest way to get from Louisville to Key West is to fly which takes 6h 25m and costs $130 - $700.
No, there is no direct bus from Louisville to Key West. However, there are services departing from Louisville, KY and arriving at N Roosevelt & 3rd Street via Nashville Bus Station, Atlanta Bus Station, Miami Airport Station and Big Pine Key - CVS / MM30. The journey, including transfers, takes approximately 30h 26m.
The distance between Louisville and Key West is 985 miles. The road distance is 1182 miles.
The best way to get from Louisville to Key West without a car is to bus and ferry which takes 28h 26m and costs $350 - $550.
It takes approximately 6h 25m to get from Louisville to Key West, including transfers.
Louisville to Key West bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Key West is to fly which takes 6h 25m and costs $130 - $700. Alternatively, you can bus, which costs $150 - $370 and takes 30h 26m.
Louisville to Key West bus services, operated by Amtrak Thruway, arrive at Nashville station.
Yes, the driving distance between Louisville to Key West is 1182 miles. It takes approximately 21h 52m to drive from Louisville to Key West.
What companies run services between Louisville, KY, USA and Key West, FL, USA?
Delta, American Airlines, and two other airlines fly from Louisville International Airport (SDF) to Key West International Airport (EYW) every 4 hours. Alternatively, you can take a bus from Louisville, KY to N Roosevelt & 3rd Street via Nashville Bus Station, Atlanta Bus Station, Miami Airport Station, Big Pine Key, and Big Pine Key - CVS / MM30 in around 30h 26m.
- Website
- delta.com
Flights from Louisville International Airport to Key West International Airport via Atlanta
- Ave. Duration
- 5h 30m
- When
- Every day
- Estimated price
- $130–650
Flights from Evansville to Key West International Airport via Atlanta
- Ave. Duration
- 4h 49m
- When
- Every day
- Estimated price
- $150–800
Flights from Covington to Key West International Airport via Atlanta
- Ave. Duration
- 5h 4m
- When
- Every day
- Estimated price
- $160–800
- Website
- aa.com
Flights from Louisville International Airport to Key West International Airport via Miami
- Ave. Duration
- 6h 6m
- When
- Monday, Tuesday, Wednesday, Thursday, Friday, and Sunday
- Estimated price
- $140–700
Flights from Evansville to Key West International Airport via Charlotte
- Ave. Duration
- 5h 57m
- When
- Every day
- Estimated price
- $170–850
Flights from Evansville to Key West International Airport via Dallas/Ft.Worth
- Ave. Duration
- 9h 6m
- When
- Every day
- Estimated price
- $230–1,000
Flights from Evansville to Key West International Airport via Chicago O'Hare
- Ave. Duration
- 9h 53m
- When
- Monday, Tuesday, Thursday, Friday, Saturday, and Sunday
- Estimated price
- $210–950
Flights from Covington to Key West International Airport via Miami
- Ave. Duration
- 4h 58m
- When
- Monday, Tuesday, Thursday, Friday, and Sunday
- Estimated price
- $170–850
- Website
- allegiantair.com
Flights from Evansville to Key West International Airport via St. Petersburg
- Ave. Duration
- 5h 10m
- When
- Wednesday
- Estimated price
- $150–800
Flights from Covington to Key West International Airport
- Ave. Duration
- 2h 39m
- When
- Monday, Wednesday, and Saturday
- Estimated price
- $160–800
- Website
- spirit.com
Flights from Louisville International Airport to Key West International Airport via Fort Lauderdale
- Ave. Duration
- 6h 15m
- When
- Every day
- Estimated price
- $120–650
- Website
- flybreeze.com
Flights from Louisville International Airport to Key West International Airport via Tampa
- Ave. Duration
- 10h 18m
- When
- Thursday and Sunday
- Estimated price
- $280–1,200
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Nashville
- Ave. Duration
- 3h
- Frequency
- Twice daily
- Estimated price
- $30–50
- Website
- https://www.amtrak.com/home.html
- Adult
- $30–50
Rome2Rio's guide to Greyhound USA
Contact Details
- Phone
- +1 214-849-8100
- ifsr@greyhound.com
- Website
- greyhound.com
Bus from Nashville Bus Station to Tallahassee
- Ave. Duration
- 9h 25m
- Frequency
- Once daily
- Estimated price
- $80–190
- Website
- https://www.greyhound.com/
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 30m
- Frequency
- Every 4 hours
- Estimated price
- $35–80
- Website
- https://www.greyhound.com/
Bus from Atlanta Bus Station to Miami Airport Station
- Ave. Duration
- 14h 5m
- Frequency
- Once daily
- Estimated price
- $65–200
- Website
- https://www.greyhound.com/
Bus from Miami Airport Station to Big Pine Key
- Ave. Duration
- 3h 35m
- Frequency
- 3 times a day
- Estimated price
- $22–40
- Website
- https://www.greyhound.com/
- Phone
- +1 800-923-1799
- contactus@omexusa.net
- Website
- omnibusexpress.com
Bus from Tallahassee to Fort Myers
- Ave. Duration
- 7h 56m
- Frequency
- Once daily
- Estimated price
- $80–110
- Schedules at
- omnibusexpress.com
- Phone
- +1 502-368-5644 x 135
- Website
- ridewithmiller.com
Bus from Louisville, KY to Evansville, IN
- Ave. Duration
- 2h 20m
- Frequency
- Once daily
- Estimated price
- $35–55
- Website
- https://ridewithmiller.com
- Phone
- +1 888-378-3823
- info@baronsbus.com
- Website
- baronsbus.com
Bus from Louisville, KY Bus Station to Cincinnati - Downtown
- Ave. Duration
- 1h 52m
- Frequency
- Once daily
- Estimated price
- $9–45
- Website
- https://baronsbus.com
- Phone
- +1 (855) 626-8585
- Website
- flixbus.com
Bus from Nashville Bus Station to Atlanta Bus Station
- Ave. Duration
- 4h 10m
- Frequency
- 3 times a day
- Estimated price
- $35–70
- Schedules at
- flixbus.com
- Phone
- +1 305-809-3700
- Website
- cityofkeywest-fl.gov
Bus from Big Pine Key - CVS / MM30 to N Roosevelt & 3rd Street
- Ave. Duration
- 1h 9m
- Frequency
- Every 3 hours
- Estimated price
- $2–4
- Schedules at
- https://www.cityofkeywest-fl.gov/595/Schedules-and-Route-Maps
- Phone
- +1 239-463-5733
- Website
- keywestexpress.net
Ferry from Fort Myers Beach, FL to Key West, FL
- Ave. Duration
- 4h
- Frequency
- Once daily
- Estimated price
- $130
- Website
- https://www.keywestexpress.net
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