There are 5 ways to get from Louisville to Chicago by plane, bus (Amtrak), bus, train, or car
Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.
Fly to Chicago Midway International Airport
best- Fly from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW)SDF - MDW
3h 24m$69–428Bus (Amtrak)
cheapest- Take the bus from Louisville, KY to Chicago Union Station
6h$50–60Bus, train (Amtrak)
- Take the bus from Louisville, KY to Indianapolis Union Station
- Take the train from Indianapolis to Chicago Union StationCardinal
8h 20m$58–344Drive 294.4 mi
- Drive from Louisville to Chicago294.4 mi
4h 59m$54–78Fly to Chicago O'Hare International Airport
- Fly from Louisville International Airport (SDF) to Chicago O'Hare International Airport (ORD)SDF - ORD
3h 54m$204–558
Louisville to Chicago by bus (Amtrak)
Questions & Answers
The cheapest way to get from Louisville to Chicago is to bus which costs $50 - $60 and takes 6h.
The fastest way to get from Louisville to Chicago is to fly which takes 3h 24m and costs $65 - $430.
Yes, there is a direct bus departing from Louisville, KY and arriving at Chicago Union Station station. Services depart twice daily, and operate every day. The journey takes approximately 6h.
The distance between Louisville and Chicago is 290 miles. The road distance is 296.1 miles.
The best way to get from Louisville to Chicago without a car is to bus which takes 6h and costs $50 - $60.
It takes approximately 3h 24m to get from Louisville to Chicago, including transfers.
Louisville to Chicago bus services, operated by Amtrak Thruway, depart from Louisville, KY station.
The best way to get from Louisville to Chicago is to fly which takes 3h 24m and costs $65 - $430. Alternatively, you can bus, which costs $50 - $60 and takes 6h.
Louisville to Chicago bus services, operated by Amtrak Thruway, arrive at Chicago Union Station.
Chicago is 1h behind Louisville. It is currently 3:26 PM in Louisville and 2:26 PM in Chicago.
What companies run services between Louisville, KY, USA and Chicago, IL, USA?
Southwest Airlines flies from Louisville International Airport (SDF) to Chicago Midway International Airport (MDW) twice daily. Alternatively, Amtrak Thruway operates a bus from Louisville, KY to Chicago Union Station twice daily. Tickets cost $50–60 and the journey takes 6h.
- Website
- southwest.com
Flights from Louisville International Airport to Chicago Midway International Airport
- Ave. Duration
- 1h 15m
- When
- Every day
- Estimated price
- $65–420
- Website
- united.com
Flights from Louisville International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $50–320
- Website
- aa.com
Flights from Louisville International Airport to Chicago O'Hare International Airport
- Ave. Duration
- 1h 43m
- When
- Every day
- Estimated price
- $50–320
Rome2Rio's guide to Amtrak
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Train from Indianapolis to Chicago Union Station
- Ave. Duration
- 5h
- Frequency
- 3 times a week
- Estimated price
- $35–300
- Website
- https://www.amtrak.com/home.html
Rome2Rio's guide to Amtrak Thruway
Contact Details
- Phone
- +1 800-872-7245
- Website
- amtrak.com
Bus from Louisville, KY to Chicago Union Station
- Ave. Duration
- 6h
- Frequency
- Twice daily
- Estimated price
- $50–60
- Website
- https://www.amtrak.com/home.html
- Adult
- $50–60
Bus from Louisville, KY to Indianapolis Union Station
- Ave. Duration
- 2h 20m
- Frequency
- Twice daily
- Estimated price
- $22–45
- Website
- https://www.amtrak.com/home.html
- Adult
- $22–45
Want to know more about travelling around United States
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More Questions & Answers
Yes, the driving distance between Louisville to Chicago is 296 miles. It takes approximately 4h 59m to drive from Louisville to Chicago.
Book your Louisville to Chicago bus tickets online with Omio.
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