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How to get fromKnoxville to Pittsburghby plane, bus, train, car or bus (Flixbus)

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There are 7 ways to get from Knoxville to Pittsburgh by plane, bus, train, car, or bus (Flixbus)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly from Mcghee Tyson Airport

    best
    1. Fly from Mcghee Tyson Airport (TYS) to Pittsburgh International Airport (PIT)planeTYS - PIT
    5h 25m
    $157–667

  2. Drive 487.5 mi

    cheapest
    1. Drive from Knoxville to Pittsburghcar487.5 mi
    8h 13m
    $89–129

  3. Bus, train

    1. Take the bus from Knoxville to New York CitybusNashville
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak StationtrainPennsylvanian
    24h 11m
    $200–563

  4. Drive to Nashville, fly

    1. Drive from Knoxville to Nashville-Airport-BNAcar
    2. Fly from Nashville (BNA) to Pittsburgh International Airport (PIT)planeBNA - PIT
    5h 39m
    $142–386

  5. Drive to Greenville–Spartanburg International Airport, fly

    1. Drive from Knoxville to Greenville–Spartanburg International Airport (GSP)car
    2. Fly from Greenville–Spartanburg International Airport (GSP) to Pittsburgh International Airport (PIT)planeGSP - PIT
    6h 16m
    $191–495

  6. Bus, train via Farragut

    1. Take the bus from Knoxville to New YorkbusMemphis
    2. Take the train from Ny Moynihan Train Hall At Penn Station to Pittsburgh Amtrak StationtrainPennsylvanian
    24h 12m
    $262–658

  7. Bus

    1. Take the bus from Knoxville to New York CitybusNashville
    2. Take the bus from New York City Chinatown to Pittsburgh Intermodal StationbusFlixBus N2640
    27h 4m
    $138–244

Knoxville to Pittsburgh by bus and foot

Calendar3Weekly Services
Duration27h 4mAverage Duration
Ticket$138Cheapest Price
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Questions & Answers

What companies run services between Knoxville, TN, USA and Pittsburgh, PA, USA?

Southwest Airlines, Delta, and two other airlines fly from Mcghee Tyson Airport (TYS) to Pittsburgh International Airport (PIT) every 3 hours. Alternatively, you can take a bus from Knoxville Station Bay H to Pittsburgh Intermodal Station via Fountain City Superstop, Walmart, Knoxville, and New York City Chinatown in around 27h 4m.

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