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How to get fromChicago to Charlotteby plane, bus (Flixbus, Greyhound), train (Amtrak), car, train or bus (Greyhound)

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There are 9 ways to get from Chicago to Charlotte by plane, bus (Flixbus, Greyhound), train (Amtrak), car, train, or bus (Greyhound)

Select an option below to see step-by-step directions and to compare ticket prices and travel times in Rome2Rio's travel planner.

  1. Fly Chicago O'Hare International Airport to Charlotte Douglas International Airport

    best
    1. Fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT)planeORD - CLT
    4h 28m
    $86–308

  2. Fly Chicago Midway International Airport to Charlotte Douglas International Airport

    cheapest
    1. Fly from Chicago Midway International Airport (MDW) to Charlotte Douglas International Airport (CLT)planeMDW - CLT
    4h 5m
    $76–408

  3. Bus via Columbus

    1. Take the bus from Chicago Bus Station to ColumbusbusFlixBus N2640 / ...
    2. Take the bus from Columbus - Mound St to Charlotte Bus StationbusColumbus
    18h 49m
    $90–345

  4. Train (Amtrak)

    1. Take the train from Chicago Union Station to CarytrainFloridian
    2. Take the train from Cary to Charlotte Amtrak StationtrainPiedmont / ...
    28h 19m
    $137–1,821

  5. Drive 741.8 mi

    1. Drive from Chicago to Charlottecar741.8 mi
    12h 42m
    $136–196

  6. Train to South Bend, fly to Charlotte Douglas International Airport

    1. Take the train from Van Buren St. to South Bend Airporttrain
    2. Fly from South Bend (SBN) to Charlotte Douglas International Airport (CLT)planeSBN - CLT
    5h 45m
    $111–567

  7. Train to General Mitchell International Airport, fly to Charlotte Douglas International Airport

    1. Take the train from Chicago Union Station to Milwaukeetrain
    2. Fly from General Mitchell International Airport (MKE) to Charlotte Douglas International Airport (CLT)planeMKE - CLT
    5h 55m
    $197–512

  8. Fly Chicago O'Hare International Airport to Concord

    1. Fly from Chicago O'Hare International Airport (ORD) to Concord (USA)planeORD - USA
    4h 57m
    $126–413

  9. Bus

    1. Take the bus from Chicago Bus Station to Toledo Bus StopbusGreyhound US0164
    2. Take the bus from Toledo Bus Stop to Charlotte Bus StationbusGreyhound US0140
    20h 20m
    $88–226

Chicago to Charlotte by bus

Calendar13Weekly Buses
Duration18h 49mAverage Duration
Ticket$90Cheapest Price
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Questions & Answers

What companies run services between Chicago, IL, USA and Charlotte, NC, USA?

American Airlines, Frontier Airlines, and two other airlines fly from Chicago O'Hare International Airport (ORD) to Charlotte Douglas International Airport (CLT) every 2 hours. Alternatively, you can take a bus from Chicago Bus Station to Charlotte Bus Station via Columbus, E Main St & S High St, S Grant Ave & E Mound St, and Columbus - Mound St in around 18h 49m.

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